A study released by the National Cancer Institute confirms that HPV oropharyngeal cancers have risen an astounding 225% from 1998 -2004. If this trend continues, oral cancer will become the nation’s leading HPV-related cancer within the present decade, surpassing cervical cancer. Both the medical and dental communities have been alerted to this emerging pandemic. We are still not making the inroads required with the majority of oral cancers found in the later stages. Following a comprehensive literature review, the Journal of the American Dental Association released the following statement; “On the basis of the available literature, the authors determined that a COE of mucosal lesions generally is not predictive of histologic diagnosis. The fact that OSCCs often are diagnosed at an advanced stage of disease indicates the need for improving the COE and for developing adjuncts to help detect and diagnose oral mucosal lesions”. There is an urgent need for change. Join the fight against oral cancer and become a Vx Hero with VELscope.